Denamarin 425mg/35mg Stabilized Tablets for Large Dogs 35 lbs and over, 30 CountMade in the USA from globally sourced ingredients Tablets are individually sealed in specialized moisture resistant blister packs. A liver and brain health supplement for dogs that contains S Adenosylmethionine (SAMe) and silybin. Denamarin is a liver supplement containing S ADenosylmethionine (SAMe) and silybin. SAMe has been shown to increase liver glutathione, a potent antioxidant. The SAMe in Denamarin has also been shown to help protect liver